I have no personal experience, just some reading:
Muscle Mustangs and Fast Fords did a high-rpm efi manifold comparison a year or two ago on a 302. They compared a victor efi to a TFS R and to a CHP spyder (Victor carb manifold converted). The victor efi and TFS were similar. The CHP spyder did not beat the others until over 5500 rpm. At lower RPMs, the spyder was down by as much as 50 ft-lbs. This convinced me that the spyder would only be better on an all-out race motor that spends most of its time above 5000 RPM.
For the RPM range you specify, the TFS 351W manifold with a 90mm throttle opening sounds like a perfect fit. TFS says it's RPM range is 2000-7000 RPM.
I am looking to equip my 351W with EFI also, as soon as $$ allows.
66 coupe with: 351W, Comp Cams XE262H cam, Trickflow heads, Performer RPM intake, Edelbrock 600 carb, Ford roller rockers, Hooker Super Comps, Dr. Gas X-pipe with 2-chamber delta flows, Tremec TKO, Steeda Tri-Ax, 9" rear w/ 3.70s and a True-Trac limited slip, 5-leaf rear springs, 620s front, KYBs, shelby A-arm drop, Torque-thrust IIs, autopower roll bar with retractable shoulder belts, custom dash and electrical system